Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370200 | 0.90 | BRD4 (0.37) | BRD4KMT2AMEN1MAPTF11 | |
| SCHEMBL370635 | 0.86 | BRD4 (0.40) | BRD4KMT2AMEN1MAPTTDP1 | |
| SCHEMBL370383 | 0.81 | CYP1A2 (0.36) | KMT2AMEN1F11KDM4EHTT | |
| SCHEMBL368800 | 0.81 | FFAR1 (0.35) | KMT2AKDM4EHTTTDP1CYP1A2 | |
| SCHEMBL370636 | 0.80 | BRD4 (0.37) | BRD4LMNA | |
| SCHEMBL369275 | 0.80 | P2RX3 (0.39) | KDM4ETDP1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL1390419 | 0.79 | LMNA (0.43) | KMT2AMEN1MAPTCYP1A2CYP2C19 | |
| SCHEMBL368801 | 0.76 | P2RX3 (0.42) | LMNA | |
| SCHEMBL370348 | 0.76 | MRGPRX4 (0.42) | BRD4 | |
| Formic Acid SCHEMBL27924258 | 0.74 | BRD4 (0.39) | BRD4KMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |