Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140262 | 0.92 | KMT2A (0.58) | MGLLLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL15317853 | 0.83 | FAAH (0.59) | MGLLLMNAPOLBALDH1A1HPGD | |
| SCHEMBL11478927 | 0.82 | CA12 (0.67) | MGLLLMNAPOLBALDH1A1CA12 | |
| SCHEMBL18844320 | 0.78 | KMT2A (0.60) | MGLLLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL112959 | 0.77 | MGLL (1.00) | MGLLALDH1A1HPGDTDP1 | |
| SCHEMBL24415723 | 0.76 | MGLL (0.48) | MGLLPOLBALDH1A1KDM4ECYP1A2 | |
| SCHEMBL860679 | 0.76 | LMNA (0.47) | LMNAPOLBCA12CA1CA9 | |
| SCHEMBL11745569 | 0.76 | MGLL (0.53) | MGLLLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL1949985 | 0.76 | LMNA (0.64) | MGLLLMNAPOLBALDH1A1HPGD | |
| SCHEMBL18211463 | 0.75 | MGLL (0.62) | MGLLLMNAPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019025099-A1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2019-02-07 | — | — | WO | disclosed |
| EP-2428535-A1 | THERMOSETTING POLYIMIDE RESIN COMPOSITION, CURED PRODUCT, AND ADHESIVE | Mitsubishi Gas Chemical Company, Inc. (JP) | 2012-03-14 | — | — | EP | disclosed |