Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MGLL | Q99685 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370333 | 0.92 | MGLL (0.62) | KMT2AMGLLLMNAALDH1A1KDM4E | |
| SCHEMBL18844320 | 0.82 | KMT2A (0.60) | KMT2AMGLLLMNAALDH1A1KDM4E | |
| SCHEMBL7200517 | 0.80 | MGLL (0.65) | KMT2AMGLLLMNAALDH1A1KDM4E | |
| SCHEMBL3841239 | 0.78 | USP2 (0.58) | KMT2ALMNAALDH1A1HPGDMEN1 | |
| SCHEMBL1696787 | 0.78 | USP2 (0.55) | KMT2AMGLLLMNAALDH1A1HPGD | |
| SCHEMBL719076 | 0.78 | KMT2A (0.64) | KMT2AMGLLLMNAALDH1A1KDM4E | |
| SCHEMBL15317853 | 0.75 | FAAH (0.59) | KMT2AMGLLLMNAALDH1A1POLB | |
| SCHEMBL721079 | 0.74 | KMT2A (0.64) | KMT2ALMNAALDH1A1KDM4EPOLB | |
| SCHEMBL31637511 | 0.74 | KMT2A (0.64) | KMT2AMGLLLMNAALDH1A1POLB | |
| SCHEMBL6140503 | 0.74 | LMNA (0.79) | KMT2AMGLLLMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182260-A1 | Process for the preparation of cyclic imides in the presence of polyphosphoric acid | MERCK PATENT GMBH (DE) | 2005-08-18 | — | — | US | disclosed |
| EP-1506173-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GmbH (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097600-A1 | METHOD FOR PRODUCING CYCLIC IMIDES IN THE PRESENCE OF POLYPHOSPHORIC ACID | MERCK PATENT GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182260-A1 | Process for the preparation of cyclic imides in the presence of polyphosphoric acid | PPIP5K2, ITPA, IPMK | KMT2A 4192/4885MGLL 3682/4885LMNA 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.