Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704482 | 0.91 | ALDH1A1 (0.42) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL5188438 | 0.86 | NPSR1 (0.39) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL7485102 | 0.85 | GLA (0.38) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL29184967 | 0.84 | NPSR1 (0.38) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL2871065 | 0.82 | CHRNB2 (0.41) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL17586310 | 0.81 | — | — | |
| Isothiocyanate SCHEMBL27733961 | 0.81 | ALDH1A1 (0.40) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL25891422 | 0.81 | HSD11B1 (0.41) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL30706809 | 0.80 | GLA (0.37) | GLAALDH1A1NPSR1HTTL3MBTL1 | |
| SCHEMBL9951753 | 0.79 | NPSR1 (0.38) | GLAALDH1A1NPSR1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599641-A | Cyclobutylcarboxylic acids as LPA antagonists | 百时美施贵宝公司 | 2022-06-07 | — | — | CN | disclosed |