Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645202 | 0.85 | GLA (0.40) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL3704482 | 0.81 | ALDH1A1 (0.42) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL2871065 | 0.80 | CHRNB2 (0.41) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL5188438 | 0.77 | NPSR1 (0.39) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL19808298 | 0.77 | HSD11B1 (0.37) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL25891422 | 0.76 | HSD11B1 (0.41) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29184967 | 0.75 | NPSR1 (0.38) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL21119171 | 0.73 | ALDH1A1 (0.36) | GLAALDH1A1HTTNPSR1L3MBTL1 | |
| SCHEMBL13940036 | 0.73 | GLA (0.33) | GLAALDH1A1TSHR | |
| SCHEMBL905300 | 0.73 | GLA (0.57) | GLAALDH1A1NPSR1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929547-B1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY CYCLIC AMINO ACID OR CYCL IC HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | SCHERING AG (DE) | 2002-11-27 | — | — | EP | disclosed |
| US-6265404-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-07-24 | — | — | US | disclosed |
| US-6232325-B1 | THROMBOSIS THERAPY | BERLEX LABORATORIES, INC. | 2001-05-15 | — | — | US | disclosed |
| US-6177473-B1 | FACTOR X INHIBITOR | BERLEX LABORATORIES, INC. | 2001-01-23 | — | — | US | disclosed |
| US-6008234-A | TREATING A HUMAN HAVING A DISEASE-STATE CHARACTERIZED BY THROMBOTIC ACTIVITY, INHIBITING HUMAN BLOOD COAGULATION FACTOR XA | BERLEX LABORATORIES, INC. (US) | 1999-12-28 | — | — | US | disclosed |