Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.43 |
| ▸ | THRA | P10827 | 13/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706005 | 0.91 | THRB (0.41) | THRBTHRASTAT3 | |
| SCHEMBL3706400 | 0.91 | THRB (0.52) | THRBTHRA | |
| SCHEMBL3704056 | 0.90 | THRA (0.41) | THRBTHRASTAT3 | |
| SCHEMBL3718169 | 0.86 | THRB (0.43) | THRBTHRA | |
| SCHEMBL3708160 | 0.84 | THRA (0.61) | THRBTHRA | |
| SCHEMBL3705055 | 0.83 | STAT3 (0.48) | THRBTHRASTAT3 | |
| SCHEMBL3712191 | 0.83 | THRA (0.51) | THRBTHRA | |
| SCHEMBL3706056 | 0.82 | THRA (0.40) | THRBTHRASTAT3 | |
| SCHEMBL3707780 | 0.82 | THRA (0.51) | THRBTHRA | |
| SCHEMBL3707861 | 0.81 | THRA (0.55) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |