Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 8/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 7/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710069 | 0.90 | POLB (0.47) | STAT3HPGDPRSS12F2F10 | |
| SCHEMBL3705055 | 0.90 | STAT3 (0.48) | STAT3THRBTHRAPTGES | |
| SCHEMBL3704056 | 0.85 | THRA (0.41) | STAT3THRBPRSS12THRA | |
| SCHEMBL3225769 | 0.84 | THRB (0.40) | STAT3THRBTHRAPTGES | |
| SCHEMBL3704670 | 0.83 | TSHR (0.40) | HPGDTHRBPRSS12 | |
| SCHEMBL3704908 | 0.82 | MAPT (0.39) | HPGDTHRBTHRAF2F10 | |
| SCHEMBL3710521 | 0.82 | THRB (0.46) | STAT3THRBTHRA | |
| SCHEMBL3220254 | 0.81 | KMT2A (0.38) | STAT3HPGDTHRBTHRA | |
| SCHEMBL3710141 | 0.81 | THRB (0.51) | STAT3THRBTHRAPTGES | |
| SCHEMBL3706056 | 0.80 | THRA (0.40) | STAT3THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |