Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.33 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.33 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711134 | 0.92 | LPAR1 (0.42) | LPAR1LPAR2LPAR3IP6K1IP6K3 | |
| SCHEMBL2336634 | 0.91 | LPAR1 (0.43) | LPAR1LPAR2LPAR3ALOX15CRHBP | |
| SCHEMBL3705145 | 0.90 | TLR7 (0.35) | LPAR1TLR7IP6K1IP6K3IP6K2 | |
| SCHEMBL3707582 | 0.89 | LPAR1 (0.39) | LPAR1LPAR2LPAR3ALOX15CRHBP | |
| SCHEMBL3717698 | 0.89 | P2RX3 (0.38) | LPAR1LPAR2LPAR3ALOX15CRHBP | |
| SCHEMBL3706744 | 0.87 | IP6K1 (0.43) | LPAR1LPAR2LPAR3IP6K1IP6K3 | |
| SCHEMBL2338062 | 0.87 | LPAR1 (0.38) | LPAR1LPAR2LPAR3ALOX15CRHBP | |
| SCHEMBL3704161 | 0.86 | LPAR1 (0.47) | LPAR1LPAR2LPAR3HTTIP6K1 | |
| SCHEMBL3708634 | 0.85 | ALDH1A1 (0.42) | LPAR1LPAR2LPAR3L3MBTL1PPARD | |
| SCHEMBL2339543 | 0.85 | LPAR1 (0.42) | LPAR1LPAR2LPAR3ALOX15CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |