SCHEMBL370571

SCHEMBL370571

O=C(O)c1cc(OCCCCn2c3ccccc3c3ccccc32)cc(OCCCCn2c3ccccc3c3ccccc32)c1CCOCCOCCO

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
PSEN1 P49768 7/20 0.44
PSEN2 P49810 7/20 0.44
APH1B Q8WW43 7/20 0.44
NCSTN Q92542 7/20 0.44
APH1A Q96BI3 7/20 0.44
PSENEN Q9NZ42 7/20 0.44
FABP4 P15090 2/20 0.40
FABP5 Q01469 2/20 0.40
MCL1 Q07820 2/20 0.39
BCL2 P10415 1/20 0.39
ACHE P22303 1/20 0.38
KCNA3 P22001 3/20 0.38
PLA2G2A P14555 2/20 0.38
ALDH1A1 P00352 1/20 0.37
PTK2B Q14289 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL370572 0.85 MEN1 (0.48) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL4160481 0.83 MEN1 (0.51) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL10040734 0.78 MEN1 (0.54) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL13697269 0.78 MEN1 (0.54) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL351636 0.73 FABP4 (0.55) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL4154432 0.69 PLA2G2A (0.63) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL25753066 0.68 MEN1 (1.00) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL13696968 0.68 PSEN1 (0.49) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL4160672 0.68 MEN1 (0.56) KMT2AMEN1PSEN1PSEN2APH1B
SCHEMBL3049061 0.67 MEN1 (0.96) KMT2AMEN1PSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160237305-A1 NEW TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES UNIV HOUSTON SYSTEM (US) 2016-08-18 US disclosed
US-9248467-B2 Types of electrodeposited polymer coatings with reversible wettability and electro-optical properties ADVINCULA RIGOBERTO (US) 2016-02-02 US disclosed
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-20120015146-A1 TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES THE UNIVERSITY OF HOUSTON SYSTEM (US) 2012-01-19 US disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed