SCHEMBL4154432

SCHEMBL4154432

O=C(O)c1ccc(OCCCCn2c3ccccc3c3ccccc32)cc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 2/20 0.63
PKM P14618 1/20 0.58
FABP4 P15090 2/20 0.56
FABP5 Q01469 2/20 0.56
ACHE P22303 1/20 0.56
ALDH1A1 P00352 1/20 0.56
HPGD P15428 1/20 0.56
PIN1 Q13526 1/20 0.54
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52
PSEN1 P49768 4/20 0.52
PSEN2 P49810 4/20 0.52
APH1B Q8WW43 4/20 0.52
NCSTN Q92542 4/20 0.52
APH1A Q96BI3 4/20 0.52
PSENEN Q9NZ42 4/20 0.52
PLA2G4B P0C869 1/20 0.51
KCNA3 P22001 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4154401 0.89 HRH4 (0.63) PLA2G2AFABP4FABP5ACHEALDH1A1
SCHEMBL351636 0.88 FABP4 (0.55) PLA2G2AFABP4FABP5ACHEALDH1A1
SCHEMBL4155967 0.85 MAPT (0.59) PLA2G2AFABP4FABP5ACHEALDH1A1
SCHEMBL16900271 0.85 ACHE (0.50) PLA2G2AFABP4FABP5ACHEALDH1A1
SCHEMBL13011140 0.84 ALDH1A1 (0.56) PLA2G2APKMFABP4FABP5ALDH1A1
SCHEMBL16900464 0.84 PLA2G2A (0.50) PLA2G2AFABP4FABP5ACHEPSEN1
SCHEMBL4160672 0.81 MEN1 (0.56) PLA2G2AFABP4FABP5ACHEALDH1A1
SCHEMBL19559314 0.81 MAPT (0.61) PLA2G2AFABP4FABP5ACHETSHR
SCHEMBL4730270 0.80 SMN1; SMN2 (0.56) FABP4FABP5ALDH1A1HPGDTP53
SCHEMBL1952122 0.78 TP53 (0.79) PKMALDH1A1TP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed