SCHEMBL13697269

SCHEMBL13697269

O=C(OCCOCCOCCOCCO)c1cc(OCCCCn2c3ccccc3c3ccccc32)cc(OCCCCn2c3ccccc3c3ccccc32)c1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ACHE P22303 1/20 0.43
CNR2 P34972 4/20 0.43
PSEN1 P49768 7/20 0.43
PSEN2 P49810 7/20 0.43
APH1B Q8WW43 7/20 0.43
NCSTN Q92542 7/20 0.43
APH1A Q96BI3 7/20 0.43
PSENEN Q9NZ42 7/20 0.43
FABP4 P15090 2/20 0.42
FABP5 Q01469 2/20 0.42
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
HDAC1 Q13547 3/20 0.40
HDAC6 Q9UBN7 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10040734 1.00 MEN1 (0.54) MEN1KMT2AACHECNR2PSEN1
SCHEMBL350674 0.82 PSEN1 (0.52) ACHECNR2PSEN1PSEN2APH1B
SCHEMBL351636 0.80 FABP4 (0.55) MEN1KMT2AACHECNR2PSEN1
SCHEMBL4160481 0.78 MEN1 (0.51) MEN1KMT2AACHEPSEN1PSEN2
SCHEMBL370571 0.78 KMT2A (0.48) MEN1KMT2AACHEPSEN1PSEN2
SCHEMBL370572 0.78 MEN1 (0.48) MEN1KMT2AACHEPSEN1PSEN2
SCHEMBL4151119 0.76 PSEN1 (0.47) ACHECNR2PSEN1PSEN2APH1B
SCHEMBL4725248 0.76 SCARB1 (0.52) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL13696968 0.75 PSEN1 (0.49) MEN1KMT2APSEN1PSEN2APH1B
SCHEMBL4725252 0.75 CNR2 (0.53) CNR2PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160237305-A1 NEW TYPES OF ELECTRODEPOSITED POLYMER COATINGS WITH REVERSIBLE WETTABILITY AND ELECTRO-OPTICAL PROPERTIES UNIV HOUSTON SYSTEM (US) 2016-08-18 US disclosed
US-9079999-B2 Methods for preparing polymer coatings by electrochemical grafting of polymer brushes, compositions prepared thereby and compositions for preparing the coatings ADVINCULA RIGOBERTO (US) 2015-07-14 US disclosed
US-20090236229-A1 METHODS FOR PREPARING POLYMER COATINGS BY ELECTROCHEMICAL GRAFTING OF POLYMER BRUSHES, COMPOSITIONS PREPARED THEREBY AND COMPOSITIONS FOR PREPARING THE COATINGS THE UNIVERSITY OF HOUSTON SYSTEM (US) 2009-09-24 US disclosed