Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708286 | 0.78 | KCNQ3 (0.44) | MAOAALDH1A1GAALMNAKDM4E | |
| SCHEMBL9564871 | 0.71 | HDAC1 (0.54) | ALDH1A1LMNAKDM4ESMN1; SMN2HDAC1 | |
| SCHEMBL2287134 | 0.69 | MAOA (0.68) | MAOAALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL7143357 | 0.68 | GAA (0.65) | MAOAALDH1A1GAALMNAKDM4E | |
| SCHEMBL10874378 | 0.68 | HTT (0.52) | ALDH1A1KDM4ECYP1A2CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL11695801 | 0.67 | GAA (0.63) | MAOAALDH1A1GAALMNAKDM4E | |
| SCHEMBL17815579 | 0.67 | MKNK1 (0.52) | ALDH1A1SMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL19917192 | 0.67 | MAPT (0.49) | ALDH1A1GAASMN1; SMN2HDAC1TSHR | |
| SCHEMBL3613538 | 0.66 | MAOA (0.51) | MAOAALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL16554491 | 0.66 | PTPN1 (0.55) | ALDH1A1GAALMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083645-A1 | PYRIMIDO[5,4-e][1,2,4]TRIAZINES AND USES THEREOF | SHANGHAI TARGETDRUG CO., LTD (CN) | 2010-07-29 | — | — | WO | disclosed |
| WO-2010083645-A1 | PYRIMIDO[5,4-e][1,2,4]TRIAZINES AND USES THEREOF | SHANGHAI TARGETDRUG CO., LTD (CN) | 2010-07-29 | — | — | WO | disclosed |