Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.41 |
| ▸ | THRB | P10828 | 12/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706056 | 0.92 | THRA (0.40) | THRATHRBSTAT3 | |
| SCHEMBL3707780 | 0.92 | THRA (0.51) | THRATHRB | |
| SCHEMBL3705929 | 0.90 | THRB (0.43) | THRATHRBSTAT3 | |
| SCHEMBL3702649 | 0.88 | THRA (0.42) | THRATHRB | |
| SCHEMBL3705791 | 0.85 | STAT3 (0.44) | THRATHRBSTAT3PRSS12 | |
| SCHEMBL3706005 | 0.82 | THRB (0.41) | THRATHRBSTAT3 | |
| SCHEMBL3706400 | 0.82 | THRB (0.52) | THRATHRB | |
| SCHEMBL3706682 | 0.79 | THRB (0.39) | THRATHRB | |
| SCHEMBL3703153 | 0.78 | THRB (0.45) | THRATHRB | |
| SCHEMBL3710069 | 0.78 | POLB (0.47) | STAT3PRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |