Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155106 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2ARAB9AALDH1A1GAA | |
| SCHEMBL4070775 | 0.81 | GFER (0.43) | MAPTGFERKDRMAP4K4PAK4 | |
| SCHEMBL21711411 | 0.70 | ALDH1A1 (0.40) | MAPTMEN1KMT2ARAB9AGFER | |
| SCHEMBL22941466 | 0.68 | MPO (0.43) | MAPTALDH1A1MPOLOXL2RET | |
| SCHEMBL7097939 | 0.68 | ALDH1A1 (0.44) | MEN1KMT2ARAB9AALDH1A1MPO | |
| SCHEMBL13737667 | 0.68 | ALDH1A1 (0.44) | MAPTALDH1A1MPOIDO1LOXL2 | |
| SCHEMBL4230856 | 0.68 | LMNA (0.62) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL1468357 | 0.66 | IDO1 (0.58) | ALDH1A1IDO1LOXL2TAAR1AGXT | |
| SCHEMBL16561361 | 0.66 | IDO1 (0.58) | ALDH1A1IDO1LOXL2TAAR1AGXT | |
| SCHEMBL13758676 | 0.66 | TAAR1 (0.45) | MAPTALDH1A1MPOIDO1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609669-B2 | Potassium channel modulators | ABBVIE INC. (US) | 2013-12-17 | — | — | US | disclosed |
| US-20120122888-A1 | Potassium Channel Modulators | ABBOTT LABORATORIES (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122888-A1 | Potassium Channel Modulators | KCNQ1, KCNQ2, KCNJ2 | MAPT 3131/4885MEN1 1516/4885KMT2A 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.