Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | QPCT | Q16769 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668828 | 0.88 | QPCT (0.45) | ALDH1A1QPCTLMNATBXAS1L3MBTL1 | |
| SCHEMBL3662444 | 0.81 | QPCT (0.55) | ALDH1A1QPCTLMNAL3MBTL1POLB | |
| SCHEMBL3664280 | 0.81 | QPCT (0.55) | ALDH1A1QPCTLMNAL3MBTL1POLB | |
| SCHEMBL26305930 | 0.76 | ALDH1A1 (0.45) | ALDH1A1QPCTTBXAS1L3MBTL1EGLN3 | |
| SCHEMBL3632316 | 0.76 | EGLN3 (0.43) | ALDH1A1QPCTTBXAS1POLBEGLN3 | |
| SCHEMBL3670494 | 0.75 | EGLN3 (0.46) | ALDH1A1TBXAS1EGLN3HRH4 | |
| SCHEMBL3699908 | 0.75 | ALDH1A1 (0.37) | ALDH1A1LMNAPOLBSMN1; SMN2NPC1 | |
| SCHEMBL10311722 | 0.74 | QPCT (0.50) | ALDH1A1QPCTLMNATBXAS1L3MBTL1 | |
| SCHEMBL16799114 | 0.74 | ALDH1A1 (0.61) | ALDH1A1QPCTLMNATBXAS1L3MBTL1 | |
| SCHEMBL4399230 | 0.72 | ALDH1A1 (0.54) | ALDH1A1QPCTTBXAS1L3MBTL1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170783-A1 | NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2009-07-02 | — | — | US | claimed |
| US-8541462-B2 | Tetrahydrocarbazole derivatives as ligands of G-protein coupled receptors | AETERNA ZENTARIS GMBH (DE) | 2013-09-24 | — | — | US | disclosed |
| US-20120122763-A1 | NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20090170783-A1 | NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170783-A1 | NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | GPR88, GPR34, GPR27 | ALDH1A1 1733/4885QPCT 2366/4885LMNA 3715/4885 |
| US-20120122763-A1 | NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | GPR88, GPR34, GPR27 | ALDH1A1 1733/4885QPCT 2366/4885LMNA 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.