Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 16/20 | 0.51 |
| ▸ | NPC1 | O15118 | 15/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.50 |
| ▸ | GFER | P55789 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 7/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31731985 | 0.80 | RAB9A (0.67) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL8010437 | 0.76 | ALDH1A1 (0.60) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL713889 | 0.75 | RAB9A (0.66) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL13325909 | 0.74 | RAB9A (0.83) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL13131131 | 0.73 | RAB9A (0.69) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL13325938 | 0.73 | RAB9A (0.80) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL29080554 | 0.73 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL966793 | 0.73 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL31154574 | 0.73 | RAB9A (0.74) | RAB9ANPC1KDM4EPOLBSMN1; SMN2 | |
| SCHEMBL722446 | 0.72 | CHEK1 (0.43) | RAB9ANPC1KDM4ESMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771843-B2 | Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-01 | — | — | US | disclosed |
| WO-2012007086-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | AFF2, MAPRE2, AFF4 | RAB9A 440/4885NPC1 2154/4885KDM4E 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.