Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 5/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722447 | 0.79 | NTRK1 (0.48) | CHEK1MAP2K1MAP4K4CSF1RPRKACA | |
| SCHEMBL370701 | 0.72 | RAB9A (0.51) | MAPTALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13454283 | 0.72 | NTRK1 (0.47) | CHEK1MAP2K1MAP4K4CSF1RPRKACA | |
| SCHEMBL13454268 | 0.72 | NTRK1 (0.47) | CHEK1MAP2K1MAP4K4CSF1RPRKACA | |
| SCHEMBL12920622 | 0.71 | CHEK1 (0.50) | CHEK1MAP2K1MAP4K4CSF1RPRKACA | |
| SCHEMBL103694 | 0.71 | NUDT1 (0.47) | CHEK1MAP2K1MAP4K4CSF1RPRKACA | |
| SCHEMBL715045 | 0.71 | MEN1 (0.61) | PRKACAMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13133710 | 0.71 | NTRK1 (0.46) | CHEK1MAP2K1MAP4K4CSF1RPRKACA | |
| SCHEMBL29080578 | 0.68 | FGFR1 (0.53) | CHEK1MAP2K1MAP4K4CSF1RPRKACA | |
| SCHEMBL21377621 | 0.68 | CHEK1 (0.46) | CHEK1MAP2K1MAP4K4CSF1RPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771843-B2 | Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | AFF2, MAPRE2, AFF4 | CHEK1 2371/4885MAP2K1 4022/4885MAP4K4 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.