Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.54 |
| ▸ | FPR1 | P21462 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715636 | 0.92 | ALDH1A1 (0.61) | SMN1; SMN2ALOX15FPR1KDM4EALDH1A1 | |
| SCHEMBL3703776 | 0.89 | SMN1; SMN2 (0.64) | SMN1; SMN2ALOX15FPR1KDM4EPOLB | |
| SCHEMBL3702953 | 0.83 | ALDH1A1 (0.64) | SMN1; SMN2ALOX15FPR1KDM4EPOLB | |
| SCHEMBL3709876 | 0.80 | ALDH1A1 (0.74) | SMN1; SMN2ALOX15FPR1KDM4EPOLB | |
| SCHEMBL3707512 | 0.76 | ALOX15 (0.70) | SMN1; SMN2ALOX15FPR1KDM4EPOLB | |
| SCHEMBL3711099 | 0.73 | USP7 (0.60) | SMN1; SMN2ALOX15KDM4EALDH1A1RXFP1 | |
| SCHEMBL3709481 | 0.71 | ALDH1A1 (0.66) | SMN1; SMN2ALOX15FPR1KDM4EPOLB | |
| SCHEMBL3706130 | 0.70 | ALOX15 (0.62) | ALOX15FPR1KDM4EPOLBALDH1A1 | |
| SCHEMBL6721712 | 0.69 | ALOX15 (0.74) | SMN1; SMN2ALOX15FPR1KDM4EPOLB | |
| SCHEMBL3709852 | 0.69 | MEN1 (0.59) | SMN1; SMN2ALOX15FPR1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081783-A1 | NOVEL SPECIFIC INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7, THE PHARMACEUTICAL COMPOSITIONS THEREOF AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2010-07-22 | — | — | WO | claimed |