Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704314 | 0.93 | THRB (0.44) | THRBTHRARORCUSP2LMNA | |
| SCHEMBL3711993 | 0.91 | THRB (0.45) | THRBTHRARORCUSP2LMNA | |
| SCHEMBL3706682 | 0.91 | THRB (0.39) | THRBTHRARORCUSP2LMNA | |
| SCHEMBL3226718 | 0.88 | THRB (0.37) | THRBTHRARORC | |
| SCHEMBL3227804 | 0.85 | THRB (0.39) | THRBTHRARORC | |
| SCHEMBL3219376 | 0.85 | ALDH1A1 (0.38) | THRBTHRARORCUSP2LMNA | |
| SCHEMBL3713161 | 0.84 | THRB (0.43) | THRBTHRARORCLMNA | |
| SCHEMBL3706521 | 0.84 | RORC (0.53) | THRBTHRARORC | |
| SCHEMBL3703153 | 0.84 | THRB (0.45) | THRBTHRARORC | |
| SCHEMBL3704007 | 0.82 | THRB (0.43) | THRBTHRARORCUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |