SCHEMBL3707593

SCHEMBL3707593

CO[Si](C)(CCCNN1CCNCC1)OC

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.51
GNAO1 P09471 1/20 0.51
GNAI1 P63096 1/20 0.51
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935537 0.85 GNAI3 (0.53) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL3702867 0.84 GNAI3 (0.53) GNAI3GNAO1GNAI1
SCHEMBL3699860 0.81 KDM1A (0.33) GNAI3GNAO1GNAI1
SCHEMBL3707781 0.79 GNAI3 (0.41) GNAI3GNAO1GNAI1
SCHEMBL9420766 0.76 MEN1 (0.43) MEN1KMT2A
SCHEMBL934568 0.75 GNAI3 (0.54) GNAI3GNAO1GNAI1
SCHEMBL28915048 0.75 MEN1 (0.43) MEN1KMT2A
SCHEMBL28628630 0.75 SIGMAR1 (0.32)
SCHEMBL28915051 0.74 SIGMAR1 (0.31)
SCHEMBL775087 0.74 CXCR4 (0.44) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109401313-A A kind of Kapton and preparation method thereof 株洲时代新材料科技股份有限公司 2019-03-01 CN claimed
CN-109401313-A A kind of Kapton and preparation method thereof 株洲时代新材料科技股份有限公司 2019-03-01 CN disclosed
US-8357755-B2 Cross-linkable organosilicon-based compositions WACKER CHEMIE AG (DE) 2013-01-22 US disclosed
US-20120123048-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2012-05-17 US disclosed