SCHEMBL935537

SCHEMBL935537

CO[Si](CCCNN1CCNCC1)(OC)OC

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.53
GNAO1 P09471 2/20 0.53
GNAI1 P63096 2/20 0.53
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3707593 0.85 GNAI3 (0.51) GNAI3GNAO1GNAI1MEN1KMT2A
SCHEMBL934568 0.83 GNAI3 (0.54) GNAI3GNAO1GNAI1
SCHEMBL3712866 0.79 HTR4 (0.34) GNAI3GNAO1GNAI1
SCHEMBL935505 0.78 GNAI3 (0.42) GNAI3GNAO1GNAI1
SCHEMBL9420756 0.76 MEN1 (0.44) MEN1KMT2A
SCHEMBL3702867 0.76 GNAI3 (0.53) GNAI3GNAO1GNAI1
SCHEMBL28275509 0.75 GNAI3 (0.56) GNAI3GNAO1GNAI1
SCHEMBL28168764 0.74 HTT (0.41) MEN1KMT2A
SCHEMBL4974361 0.74 GNAO1 (0.81) GNAI3GNAO1GNAI1
SCHEMBL465021 0.73 CXCR4 (0.46) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357755-B2 Cross-linkable organosilicon-based compositions WACKER CHEMIE AG (DE) 2013-01-22 US disclosed
EP-2454326-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS Wacker Chemie AG (DE) 2012-05-23 EP disclosed
US-20120123048-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2012-05-17 US disclosed
WO-2011006808-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2011-01-20 WO disclosed