SCHEMBL934568

SCHEMBL934568

CCO[Si](CCCNN1CCNCC1)(OCC)OCC

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.54
GNAO1 P09471 2/20 0.54
GNAI1 P63096 2/20 0.54
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3702867 0.86 GNAI3 (0.53) GNAI3GNAO1GNAI1
SCHEMBL935537 0.83 GNAI3 (0.53) GNAI3GNAO1GNAI1
SCHEMBL935171 0.81 HTT (0.36) GNAI3GNAO1GNAI1
SCHEMBL936231 0.80 GNAI3 (0.43) GNAI3GNAO1GNAI1
SCHEMBL9420789 0.77 HSD17B10 (0.41) GNAI3GNAO1GNAI1
SCHEMBL3707593 0.75 GNAI3 (0.51) GNAI3GNAO1GNAI1
SCHEMBL4974361 0.75 GNAO1 (0.81) GNAI3GNAO1GNAI1HRH4
SCHEMBL2401145 0.75 CXCR4 (0.43) GNAI3GNAO1GNAI1
SCHEMBL27873396 0.74 GNAI3 (0.46) GNAI3GNAO1GNAI1HRH4
SCHEMBL4063582 0.73 CXCR4 (0.44) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357755-B2 Cross-linkable organosilicon-based compositions WACKER CHEMIE AG (DE) 2013-01-22 US disclosed
EP-2454326-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS Wacker Chemie AG (DE) 2012-05-23 EP disclosed
US-20120123048-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2012-05-17 US disclosed
WO-2011006808-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2011-01-20 WO disclosed