Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5247989 | 0.85 | RAB9A (0.42) | KDM4EGAAALDH1A1GLARAB9A | |
| SCHEMBL5249517 | 0.82 | SMN1; SMN2 (0.40) | KDM4EGAAALDH1A1GLARAB9A | |
| SCHEMBL361737 | 0.79 | KDM4E (0.44) | KDM4EGAAALDH1A1GLARAB9A | |
| SCHEMBL5593404 | 0.78 | EGLN2 (0.42) | KDM4EGAAALDH1A1GLARAB9A | |
| SCHEMBL363046 | 0.77 | ALDH1A1 (0.42) | KDM4EGAAALDH1A1GLARAB9A | |
| SCHEMBL1478123 | 0.77 | KDM4E (0.36) | KDM4EGAAALDH1A1GLARAB9A | |
| SCHEMBL8124935 | 0.74 | EGLN2 (0.44) | KDM4EGAAALDH1A1SMN1; SMN2EGLN2 | |
| SCHEMBL3704252 | 0.74 | ADORA2A (0.41) | KDM4EGAAADORA2ACCNE2CCNE1 | |
| SCHEMBL3702134 | 0.72 | AKT1 (0.40) | KDM4EGAAALDH1A1GLARAB9A | |
| SCHEMBL5249870 | 0.71 | PDE2A (0.39) | KDM4EGAAALDH1A1GLARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396330-A1 | FUSED PYRIMIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010091808-A1 | FUSED PYRIMIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-08-19 | — | — | WO | disclosed |