Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | PDE6A | P16499 | 1/20 | 0.32 |
| ▸ | PDE6G | P18545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363046 | 0.80 | ALDH1A1 (0.42) | RAB9AKDM4EALDH1A1GLAGAA | |
| SCHEMBL5593135 | 0.79 | EGLN2 (0.40) | EGLN2DPP4NISCHRAB9ANPC1 | |
| SCHEMBL5593088 | 0.78 | EGLN2 (0.34) | EGLN2DPP4NISCHPTPN11 | |
| SCHEMBL3707772 | 0.78 | KDM4E (0.43) | EGLN2RAB9AKDM4EALDH1A1GLA | |
| SCHEMBL1478123 | 0.77 | KDM4E (0.36) | EGLN2RAB9AKDM4EALDH1A1GLA | |
| SCHEMBL5420498 | 0.76 | KMT2A (0.47) | EGLN2KDM4EALDH1A1GAAHSD11B1 | |
| SCHEMBL5247989 | 0.74 | RAB9A (0.42) | EGLN2RAB9AKDM4EALDH1A1GLA | |
| SCHEMBL5249517 | 0.74 | SMN1; SMN2 (0.40) | EGLN2RAB9AKDM4EALDH1A1GLA | |
| SCHEMBL5593054 | 0.74 | PDE2A (0.34) | DPP4PDE2ACCNE1CDK2 | |
| SCHEMBL361737 | 0.71 | KDM4E (0.44) | RAB9AKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007101871-A1 | SUBSTITUTED IMIDAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER | BASF SE (DE) | 2007-09-13 | — | — | WO | disclosed |