Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338062 | 0.96 | LPAR1 (0.38) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3709586 | 0.94 | LPAR1 (0.38) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3708660 | 0.93 | LPAR1 (0.40) | PPARDLPAR1LPAR2LPAR3MAPT | |
| SCHEMBL3714488 | 0.93 | L3MBTL1 (0.34) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3713874 | 0.90 | L3MBTL1 (0.37) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3713473 | 0.89 | PPARD (0.39) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL2335497 | 0.89 | LPAR1 (0.45) | PPARDLPAR1LPAR2LPAR3 | |
| SCHEMBL3713548 | 0.88 | LPAR1 (0.37) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3704850 | 0.88 | GPBAR1 (0.34) | HTTNPC1RAB9AALDH1A1PPARD | |
| SCHEMBL3717656 | 0.88 | KMT2A (0.34) | L3MBTL1HTTSMN1; SMN2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |