Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705512 | 0.94 | LPAR1 (0.39) | LPAR1LPAR2LPAR3CYP11B1CYP11B2 | |
| SCHEMBL3707844 | 0.93 | L3MBTL1 (0.38) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3709586 | 0.90 | LPAR1 (0.38) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL2338062 | 0.88 | LPAR1 (0.38) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3707271 | 0.87 | PDE4B (0.38) | CYP2C9CYP2C19 | |
| SCHEMBL3707597 | 0.87 | LPAR1 (0.46) | LPAR1LPAR2LPAR3CYP11B1CYP11B2 | |
| SCHEMBL3706374 | 0.86 | MDM2 (0.39) | L3MBTL1ALOX15CRHBPHTTCRHR2 | |
| SCHEMBL3708660 | 0.86 | LPAR1 (0.40) | LPAR1LPAR2LPAR3MAPT | |
| SCHEMBL3702769 | 0.85 | S1PR1 (0.38) | CYP11B1CYP11B2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3713874 | 0.85 | L3MBTL1 (0.37) | L3MBTL1ALOX15CRHBPHTTCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |