Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3715785 | 0.95 | HPGD (0.34) | KMT2AGAATSHRHSD17B10HPGD | |
| SCHEMBL3707177 | 0.94 | LPAR1 (0.34) | HPGDSMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL2338259 | 0.89 | LPAR1 (0.39) | HPGDSMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL3709586 | 0.88 | LPAR1 (0.38) | HPGDSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL3713874 | 0.88 | L3MBTL1 (0.37) | KMT2AGAATSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL3704850 | 0.88 | GPBAR1 (0.34) | TSHRHPGDALDH1A1POLBHTT | |
| SCHEMBL3707844 | 0.88 | L3MBTL1 (0.38) | SMN1; SMN2ALDH1A1HTTMAPTRAB9A | |
| SCHEMBL3712011 | 0.85 | PKM (0.43) | KMT2ATSHRHPGDSMN1; SMN2KDM4E | |
| SCHEMBL2338062 | 0.85 | LPAR1 (0.38) | HPGDSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL2334024 | 0.85 | L3MBTL1 (0.38) | KMT2AGAATSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |