Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HTR7 | P34969 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705960 | 0.91 | HTR7 (0.65) | KDM4EHTR7KMT2AALDH1A1MEN1 | |
| SCHEMBL3708205 | 0.88 | C5AR1 (0.61) | KDM4EHTR7KMT2AALDH1A1MEN1 | |
| SCHEMBL3563737 | 0.88 | KDM4E (0.64) | KDM4EHTR7KMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL3703420 | 0.87 | C5AR1 (0.60) | KDM4EHTR7KMT2AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL3710903 | 0.86 | KDM4E (0.62) | KDM4EHTR7KMT2AALDH1A1MEN1 | |
| SCHEMBL3704117 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1HTTTDP1DRD2 | |
| SCHEMBL26418370 | 0.79 | DRD2 (0.71) | KDM4EALDH1A1LMNAHTTTDP1 | |
| SCHEMBL14529139 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1HTTTDP1DRD2 | |
| Hydrochloric Acid SCHEMBL3710255 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1HTTTDP1DRD2 | |
| SCHEMBL3556792 | 0.78 | DRD2 (0.68) | KDM4EALDH1A1LMNAHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |