Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711675 | 0.82 | MEN1 (0.33) | — | |
| SCHEMBL3704892 | 0.78 | MEN1 (0.31) | — | |
| SCHEMBL3017563 | 0.65 | OPRM1 (0.42) | — | |
| SCHEMBL11642526 | 0.63 | CACNA1F (0.36) | MAOBMAOA | |
| SCHEMBL13598559 | 0.62 | MAOB (0.50) | MAOBMAOA | |
| SCHEMBL8942090 | 0.61 | HTR2A (0.45) | — | |
| SCHEMBL3712955 | 0.61 | MAPT (0.32) | — | |
| SCHEMBL8942143 | 0.59 | KMT2A (0.42) | — | |
| SCHEMBL25421886 | 0.59 | — | — | |
| SCHEMBL17018491 | 0.58 | MAOA (0.45) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391603-A1 | AROYLAMINO - AND HETEROAROYLAMINO-SUBSTITUTED PIPERIDINES AS GLYT-1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2011-12-07 | — | — | EP | disclosed |
| WO-2010086251-A1 | AROYLAMINO - AND HETEROAROYLAMINO-SUBSTITUTED PIPERIDINES AS GLYT-1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-08-05 | — | — | WO | disclosed |