Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3009122 | 0.90 | APEX1 (0.50) | CYP19A1APEX1DHODHXDHKMT2A | |
| SCHEMBL3704905 | 0.89 | CYP19A1 (0.44) | CYP19A1CDC7F2APEX1DHODH | |
| SCHEMBL31738617 | 0.83 | ALOX5 (0.52) | KMT2AFBP1CYP3A4SMN1; SMN2 | |
| SCHEMBL31022359 | 0.81 | ALDH1A1 (0.45) | CYP19A1APEX1XDHKMT2AFBP1 | |
| SCHEMBL3004155 | 0.81 | TUBB4A (0.48) | CYP19A1XDHPKMKMT2ACRHBP | |
| SCHEMBL31738623 | 0.80 | RIPK1 (0.47) | CYP19A1XDHKMT2AFBP1RIPK1 | |
| SCHEMBL3004133 | 0.80 | CYP19A1 (0.50) | CYP19A1APEX1DHODHXDHKMT2A | |
| SCHEMBL3725136 | 0.79 | TUBB4A (0.46) | APEX1XDHPKMKMT2AFBP1 | |
| SCHEMBL31022578 | 0.79 | CYP19A1 (0.49) | CYP19A1APEX1DHODHXDHERN1 | |
| SCHEMBL3010855 | 0.79 | CYP19A1 (0.49) | CYP19A1APEX1DHODHXDHPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |