SCHEMBL3703408

SCHEMBL3703408

CCOC(OCC)[SiH2]CNN1CCOCC1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3707562 0.83 HTR4 (0.32)
SCHEMBL3708780 0.80 GNAI3 (0.40)
SCHEMBL935599 0.74 TSHR (0.34) TSHRKMT2AALDH1A1LMNAMAPT
SCHEMBL2413668 0.74 USP2 (0.35) TSHRKMT2AALDH1A1LMNAMAPT
SCHEMBL31468523 0.69 ALDH1A1 (0.42) TSHRALDH1A1LMNAHPGD
SCHEMBL658288 0.67
SCHEMBL555286 0.67 THRB (0.36) LMNA
SCHEMBL3709886 0.67 ALDH1A1 (0.35) KMT2AALDH1A1LMNAMAPTHPGD
Hydrochloric Acid SCHEMBL28159570 0.65 HTT (0.42) TSHRKMT2AALDH1A1LMNARAB9A
SCHEMBL15062569 0.64 THRB (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357755-B2 Cross-linkable organosilicon-based compositions WACKER CHEMIE AG (DE) 2013-01-22 US disclosed
US-20120123048-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2012-05-17 US disclosed