Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 9/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 9/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708411 | 0.88 | SMN1; SMN2 (0.46) | KDM4EMAPTALDH1A1 | |
| SCHEMBL3707319 | 0.83 | CDC7 (0.44) | CDC7DBF4TRPM8DHODHKDM4E | |
| SCHEMBL3710384 | 0.80 | CDC7 (0.48) | CDC7DBF4TRPM8DHODHKDM4E | |
| SCHEMBL8867336 | 0.77 | CDC7 (0.62) | CDC7DBF4TRPM8DHODHKDM4E | |
| SCHEMBL28297244 | 0.74 | CDC7 (0.65) | CDC7DBF4TRPM8DHODHKDM4E | |
| SCHEMBL8867093 | 0.71 | CDC7 (0.62) | CDC7DBF4TRPM8DHODHKDM4E | |
| SCHEMBL1982927 | 0.71 | XDH (0.54) | CDC7DBF4TRPM8KDM4EALDH1A1 | |
| SCHEMBL3704896 | 0.71 | SMN1; SMN2 (0.43) | KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL23794638 | 0.70 | TRPM8 (0.80) | CDC7DBF4TRPM8KDM4EMAPT | |
| SCHEMBL3712683 | 0.70 | CDC7 (0.48) | CDC7DBF4TRPM8DHODHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |