Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479346 | 0.95 | RXFP1 (0.35) | RXFP1CSF1RMAPTNPC1RAB9A | |
| SCHEMBL479687 | 0.93 | TGM2 (0.34) | CSF1RALDH1A1L3MBTL1TGM2TP53 | |
| SCHEMBL479775 | 0.89 | TGM2 (0.33) | CSF1RTGM2KDRAURKBFLT3 | |
| SCHEMBL3709540 | 0.88 | LMNA (0.38) | RXFP1CSF1RMAPTNPC1RAB9A | |
| SCHEMBL479370 | 0.85 | AURKA (0.36) | CSF1RALDH1A1TGM2KDRAURKB | |
| SCHEMBL479559 | 0.85 | RXFP1 (0.41) | RXFP1CSF1RMAPTNPC1RAB9A | |
| SCHEMBL479345 | 0.84 | LMNA (0.40) | RXFP1CSF1RMAPTNPC1RAB9A | |
| SCHEMBL479340 | 0.83 | RXFP1 (0.36) | RXFP1CSF1RMAPTNPC1RAB9A | |
| SCHEMBL2119767 | 0.82 | RXFP1 (0.42) | RXFP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2121822 | 0.81 | RXFP1 (0.41) | RXFP1MAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |