Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CSF1R | P07333 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479770 | 0.92 | KMT2A (0.40) | CSF1RTP53THRBAURKBTGM2 | |
| SCHEMBL479847 | 0.86 | PDPK1 (0.39) | CSF1RTP53THRBAURKBKDR | |
| SCHEMBL479793 | 0.85 | ALDH1A1 (0.46) | RXFP1MAPTCSF1RTP53THRB | |
| SCHEMBL479557 | 0.85 | MAPT (0.41) | RXFP1MAPTCSF1RTP53THRB | |
| SCHEMBL479340 | 0.85 | RXFP1 (0.36) | RXFP1MAPTCSF1RTP53THRB | |
| SCHEMBL3709544 | 0.85 | RXFP1 (0.36) | RXFP1MAPTCSF1RTP53THRB | |
| SCHEMBL479289 | 0.82 | RAB9A (0.39) | RXFP1MAPTCSF1RTP53THRB | |
| SCHEMBL479346 | 0.80 | RXFP1 (0.35) | RXFP1MAPTCSF1RTP53THRB | |
| SCHEMBL479406 | 0.80 | PIM1 (0.43) | AURKBKDRTGM2MEN1KMT2A | |
| SCHEMBL479405 | 0.80 | PIM1 (0.43) | AURKBKDRTGM2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |