Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479888 | 0.89 | POLB (0.36) | CSF1RMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL479339 | 0.88 | MAPT (0.36) | RXFP1CSF1RMAPTUSP2MEN1 | |
| SCHEMBL479427 | 0.88 | ALDH1A1 (0.40) | RXFP1CSF1RMAPTUSP2MEN1 | |
| SCHEMBL479559 | 0.85 | RXFP1 (0.41) | RXFP1CSF1RMAPTMEN1KMT2A | |
| SCHEMBL3709544 | 0.83 | RXFP1 (0.36) | RXFP1CSF1RMAPTMEN1KMT2A | |
| SCHEMBL2119206 | 0.81 | RXFP1 (0.41) | RXFP1MAPTUSP2MEN1KMT2A | |
| SCHEMBL479289 | 0.80 | RAB9A (0.39) | RXFP1CSF1RMAPTMEN1KMT2A | |
| SCHEMBL480699 | 0.79 | RXFP1 (0.40) | RXFP1MAPTUSP2MEN1KMT2A | |
| SCHEMBL479346 | 0.79 | RXFP1 (0.35) | RXFP1CSF1RMAPTALDH1A1NPC1 | |
| SCHEMBL479557 | 0.79 | MAPT (0.41) | RXFP1CSF1RMAPTUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |