Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700669 | 0.92 | NR1H4 (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1GAA | |
| SCHEMBL3710883 | 0.82 | NR1H4 (0.48) | MAPTLMNAHPGDNR1H4SMPD1 | |
| SCHEMBL3709661 | 0.81 | LPAR1 (0.41) | MAPTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL3702204 | 0.81 | TP53 (0.38) | MAPTRAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3708634 | 0.81 | ALDH1A1 (0.42) | RAB9ANPC1ALDH1A1NR1H4SMPD1 | |
| SCHEMBL2335539 | 0.80 | LPAR1 (0.45) | MAPTLMNAKDM4EGAANR1H4 | |
| SCHEMBL2335475 | 0.80 | KDM4E (0.39) | MAPTRAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3715778 | 0.79 | KDM4E (0.38) | MAPTRAB9ASMN1; SMN2KMT2ANPC1 | |
| SCHEMBL3712524 | 0.79 | LPAR1 (0.42) | MAPTLMNAALDH1A1KDM4EGAA | |
| SCHEMBL3702563 | 0.79 | NR1H4 (0.46) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |