Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935171 | 0.87 | HTT (0.36) | HTTGNAI3GNAO1GNAI1KDM1A | |
| SCHEMBL3699860 | 0.83 | KDM1A (0.33) | HTTGNAI3GNAO1GNAI1KDM1A | |
| SCHEMBL3702867 | 0.83 | GNAI3 (0.53) | GNAI3GNAO1GNAI1 | |
| SCHEMBL3703407 | 0.80 | TSHR (0.34) | HTTMAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3712866 | 0.77 | HTR4 (0.34) | HTTGNAI3GNAO1GNAI1KDM1A | |
| SCHEMBL4721218 | 0.75 | HTT (0.49) | HTTGNAI3GNAO1GNAI1KDM1A | |
| SCHEMBL612357 | 0.75 | SMN1; SMN2 (0.46) | HTTMAPK1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL2616718 | 0.73 | TDP1 (0.49) | SMN1; SMN2TSHRALDH1A1GAA | |
| SCHEMBL935658 | 0.73 | TSHR (0.34) | HTTMAPK1SMN1; SMN2TSHRALDH1A1 | |
| Hydrazine SCHEMBL8557171 | 0.72 | HTT (0.46) | HTTGNAI3GNAO1GNAI1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357755-B2 | Cross-linkable organosilicon-based compositions | WACKER CHEMIE AG (DE) | 2013-01-22 | — | — | US | disclosed |
| US-20120123048-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | WACKER CHEMIE AG (DE) | 2012-05-17 | — | — | US | disclosed |