Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL935658 | 0.85 | TSHR (0.34) | TSHRSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL3707560 | 0.81 | HTR4 (0.34) | SMN1; SMN2ALDH1A1LIPEHTR4 | |
| SCHEMBL3708779 | 0.80 | GNAI3 (0.42) | — | |
| SCHEMBL3709883 | 0.80 | HTT (0.36) | TSHRSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL3706388 | 0.73 | HTR4 (0.34) | ALDH1A1LIPEHTR4 | |
| SCHEMBL935171 | 0.73 | HTT (0.36) | TSHRSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL776777 | 0.72 | TSHR (0.38) | TSHRSMN1; SMN2MAPK1KMT2AMEN1 | |
| SCHEMBL658288 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28159570 | 0.69 | HTT (0.42) | TSHRMAPK1KMT2AMEN1GAA | |
| SCHEMBL2744386 | 0.67 | KDM1A (0.40) | TSHRSMN1; SMN2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357755-B2 | Cross-linkable organosilicon-based compositions | WACKER CHEMIE AG (DE) | 2013-01-22 | — | — | US | disclosed |
| US-20120123048-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | WACKER CHEMIE AG (DE) | 2012-05-17 | — | — | US | disclosed |