Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417952 | 1.00 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDALDH3A1HTT | |
| SCHEMBL3202573 | 0.84 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL301933 | 0.82 | ALDH1A1 (0.69) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL11270639 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRHPGDALDH3A1HTT | |
| SCHEMBL29437308 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL10338964 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL124981 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL1150551 | 0.80 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDHTTHSD17B10 | |
| SCHEMBL13767679 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDALDH3A1HTT | |
| SCHEMBL249952 | 0.78 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103420892-A | Preparation method of 4-fluoroindole | ASCEPION PHARMACEUTICALS INC | 2013-12-04 | — | — | CN | claimed |
| WO-2024092235-A2 | SUBSTITUTED PHENYLBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | NINE SQUARE THERAPEUTICS CORPORATION (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024023129-A1 | NOVEL 7-SUBSTITUTED INDOLE SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-01 | — | — | WO | disclosed |
| CN-114105722-B | Method for preparing organic fluorine compound | 浙江工业大学 | 2023-10-20 | — | — | CN | disclosed |
| EP-4146644-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2023-03-15 | — | — | EP | disclosed |
| CN-114105722-A | Method for preparing organic fluorine compound | 浙江工业大学 | 2022-03-01 | — | — | CN | disclosed |
| WO-2021226003-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME CORP. (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-3466953-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE AS JANUS KINASE INHIBITOR | INCYTE HOLDINGS CORP (US) | 2021-02-03 | — | — | EP | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| EP-2391603-A1 | AROYLAMINO - AND HETEROAROYLAMINO-SUBSTITUTED PIPERIDINES AS GLYT-1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2011-12-07 | — | — | EP | disclosed |
| CN-1946680-B | Non-nucleoside reverse transcriptase inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 2011-04-06 | — | — | CN | disclosed |
| WO-2010086251-A1 | AROYLAMINO - AND HETEROAROYLAMINO-SUBSTITUTED PIPERIDINES AS GLYT-1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-08-05 | — | — | WO | disclosed |
| CN-101321736-A | To M1Compounds with receptor activity and their use in medicine | GLAXO GROUP LTD (GB) | 2008-12-10 | — | — | CN | disclosed |
| CN-1863789-A | Substituted isoquinolinones | PORTOLA PHARM INC (US) | 2006-11-15 | — | — | CN | disclosed |
| EP-1066283-A2 | SUBSTITUTED INDOLEALKANOIC ACIDS | The Institutes for Pharmaceutical Discovery, Inc. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999050268-A2 | SUBSTITUTED INDOLEALKANOIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, INC. (US) | 1999-10-07 | — | — | WO | disclosed |
| CN-1193278-A | Chemical compounds | ZENECA LTD (GB) | 1998-09-16 | — | — | CN | disclosed |
| US-5059731-A | Selectively hydrogenating acetylenic and diolefinic hydrocarbons | EUROPEANE DE RETRAITEMENT DE CATALYSEURS EURECAT (FR) | 1991-10-22 | — | — | US | disclosed |
| US-4051168-A | TO FORM FLUOROALKYL AROMATIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-09-27 | — | — | US | disclosed |