SCHEMBL3711223

SCHEMBL3711223

O=S(=O)(O)c1ccc2nnsc2c1Cl.[KH]

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BAZ1A Q9NRL2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
COMT P21964 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3702344 0.98 BAZ1A (0.32) BAZ1AMEN1NPC1RAB9AKMT2A
SCHEMBL3701490 0.97 BAZ1A (0.31) BAZ1AMEN1NPC1RAB9AKMT2A
SCHEMBL3695198 0.97 BAZ1A (0.31) BAZ1AMEN1NPC1RAB9AKMT2A
Lithium Ion SCHEMBL3701488 0.81 LMNA (0.30) KMT2A
Potassium Ion SCHEMBL3711222 0.81 RAD51 (0.33) KMT2A
SCHEMBL3704781 0.74 ALDH1A1 (0.38) BAZ1AMEN1NPC1RAB9AKMT2A
SCHEMBL1955906 0.65 CYP3A4 (0.46) COMT
SCHEMBL3701133 0.65 NOTUM (0.33)
SCHEMBL8049666 0.65 ALDH1A1 (0.41) BAZ1AMEN1NPC1RAB9AKMT2A
SCHEMBL8338086 0.63 TDP1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460789-B1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-04-19 EP disclosed
US-9079830-B2 Method for producing biaryl compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-14 US disclosed
EP-2460789-A1 METHOD FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2012-06-06 EP disclosed
US-20120123154-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120123154-A1 METHOD FOR PRODUCING BIARYL COMPOUND AKR7A2, AOC2, CBR1 BAZ1A 24/4885MEN1 1674/4885NPC1 1442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.