Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711251 | 1.00 | ABHD6 (0.52) | ABHD6ESR1ESR2NOTUMMAPT | |
| SCHEMBL5908776 | 0.93 | ABHD6 (0.59) | ABHD6ESR1ESR2NOTUMMAPT | |
| SCHEMBL5908773 | 0.93 | ABHD6 (0.59) | ABHD6ESR1ESR2NOTUMMAPT | |
| SCHEMBL506139 | 0.90 | ESR1 (0.59) | ABHD6ESR1ESR2NOTUMMAPT | |
| SCHEMBL566389 | 0.82 | ESR1 (0.68) | ABHD6ESR1ESR2NOTUMMAPT | |
| SCHEMBL30263783 | 0.82 | ESR1 (0.68) | ABHD6ESR1ESR2NOTUMMAPT | |
| SCHEMBL373718 | 0.75 | ESR1 (0.58) | ABHD6ESR1ESR2 | |
| SCHEMBL7368230 | 0.75 | MTNR1B (0.50) | ESR1ESR2MEN1KMT2AACE | |
| SCHEMBL506963 | 0.74 | ESR1 (0.50) | ABHD6ESR1ESR2 | |
| SCHEMBL5424954 | 0.73 | RIPK1 (0.72) | ABHD6ESR1ESR2NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096384-A2 | FUSED BENZAZEPINES AS NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | TARGACEPT, INC. (US) | 2010-08-26 | — | — | WO | disclosed |