Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705670 | 0.80 | PIK3CD (0.43) | ALDH1A1KDM4EPIK3CDGRM1TSHR | |
| SCHEMBL7307 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10LMNATSHR | |
| SCHEMBL863915 | 0.79 | CDK5 (0.39) | ALDH1A1KDM4ERXFP1CSNK2A1MAPK1 | |
| SCHEMBL3711291 | 0.78 | ALDH1A1 (0.35) | ALDH1A1KDM4ERXFP1PIK3CDCSNK2A1 | |
| SCHEMBL3714054 | 0.75 | KDM4E (0.37) | ALDH1A1KDM4ERXFP1PIK3CDHSD17B10 | |
| SCHEMBL3714056 | 0.75 | KDM4E (0.37) | ALDH1A1KDM4ERXFP1PIK3CDHSD17B10 | |
| SCHEMBL7863 | 0.68 | PIK3CD (0.38) | ALDH1A1KDM4EPIK3CDHSD17B10TSHR | |
| SCHEMBL20562599 | 0.68 | MTNR1A (0.56) | MTNR1AMTNR1B | |
| SCHEMBL23291226 | 0.67 | MAPT (0.48) | ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL15184778 | 0.66 | HTR7 (0.39) | ALDH1A1KDM4ERXFP1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396315-A1 | FUSED PYRIDINE AND PYRAZINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010092340-A1 | FUSED PYRIDINE AND PYRAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-08-19 | — | — | WO | disclosed |