Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 6/20 | 0.32 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711213 | 0.84 | PYGB (0.38) | — | |
| SCHEMBL3707213 | 0.84 | LGALS1 (0.35) | CA2CA12CA1 | |
| SCHEMBL317426 | 0.67 | — | — | |
| SCHEMBL7052360 | 0.67 | — | — | |
| SCHEMBL11202658 | 0.64 | FUCA1 (0.32) | CA2CA9CA12FUCA1 | |
| SCHEMBL23541364 | 0.64 | FUCA1 (0.48) | CA2CA9CA12CA1FUCA1 | |
| SCHEMBL22923476 | 0.64 | FUCA1 (0.48) | CA2CA9CA12CA1FUCA1 | |
| SCHEMBL12556709 | 0.64 | FUCA1 (0.48) | CA2CA9CA12CA1FUCA1 | |
| SCHEMBL24862325 | 0.64 | FUCA1 (0.48) | CA2CA9CA12CA1FUCA1 | |
| SCHEMBL11962132 | 0.64 | FUCA1 (0.48) | CA2CA9CA12CA1FUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010102673-A1 | HELLEBRIN AND HELLEBRIGENIN DERIVATIVES | UNIBIOSCREEN S.A. (BE) | 2010-09-16 | — | — | WO | claimed |
| WO-2010102673-A1 | HELLEBRIN AND HELLEBRIGENIN DERIVATIVES | UNIBIOSCREEN S.A. (BE) | 2010-09-16 | — | — | WO | disclosed |