Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3712176 | 0.92 | GRM5 (0.42) | ALDH1A1CSF1RCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL3712830 | 0.92 | DEGS1 (0.44) | ALDH1A1LMNASMN1; SMN2CSF1RCYP19A1 | |
| SCHEMBL3711372 | 0.91 | ALDH1A1 (0.52) | ALDH1A1KDM4ESMN1; SMN2MAPTCSF1R | |
| SCHEMBL3713260 | 0.91 | CYP11B1 (0.48) | LMNASMN1; SMN2CSF1RCYP19A1CYP11B1 | |
| SCHEMBL3712399 | 0.90 | GRM5 (0.46) | ALDH1A1CYP19A1CYP11B1CYP11B2GRM5 | |
| SCHEMBL3711302 | 0.89 | RAB9A (0.49) | LMNASMN1; SMN2MAPTCSF1RHPGD | |
| SCHEMBL3716726 | 0.88 | CSF1R (0.41) | ALDH1A1LMNASMN1; SMN2CSF1RCYP19A1 | |
| SCHEMBL3714333 | 0.88 | HDAC1 (0.49) | ALDH1A1LMNASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL3713498 | 0.88 | CYP19A1 (0.39) | ALDH1A1LMNASMN1; SMN2CSF1RCYP19A1 | |
| SCHEMBL3710087 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |