Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.35 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709661 | 0.93 | LPAR1 (0.41) | NR3C1SRD5A2KDM4EALDH1A1HPGD | |
| SCHEMBL3705375 | 0.92 | TP53 (0.37) | P2RX3PTGS2KDM4EALDH1A1HPGD | |
| SCHEMBL3702549 | 0.90 | LPAR1 (0.39) | NR3C1P2RX3SRD5A2PTGS2KDM4E | |
| SCHEMBL3713385 | 0.89 | PLA2G10 (0.38) | KDM4ETP53FFAR1LPAR1MAPT | |
| SCHEMBL2335539 | 0.87 | LPAR1 (0.45) | KDM4ETP53LPAR1MAPT | |
| SCHEMBL1247556 | 0.87 | KDM4E (0.40) | NR3C1SRD5A2KDM4ETP53FFAR1 | |
| SCHEMBL3706560 | 0.86 | KDM4E (0.36) | KDM4ETP53FFAR1LPAR1MAPT | |
| SCHEMBL3702204 | 0.86 | TP53 (0.38) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL3712524 | 0.86 | LPAR1 (0.42) | KDM4EALDH1A1TP53LPAR1MAPT | |
| SCHEMBL3714006 | 0.85 | LPAR1 (0.37) | KDM4ETP53FFAR1LPAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |