Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701871 | 0.94 | KDM4E (0.34) | KDM4EUSP2POLBTP53MAPT | |
| SCHEMBL3702315 | 0.93 | LPAR1 (0.40) | KDM4ELPAR1USP2POLBLPAR2 | |
| SCHEMBL3713385 | 0.88 | PLA2G10 (0.38) | KDM4ELPAR1USP2POLBLPAR2 | |
| SCHEMBL3703222 | 0.88 | LPAR1 (0.35) | KDM4ELPAR1USP2POLBLPAR2 | |
| SCHEMBL1247289 | 0.87 | KDM4E (0.39) | KDM4EPPARDTP53L3MBTL1 | |
| SCHEMBL3704746 | 0.87 | MMP2 (0.44) | KDM4ELPAR1USP2POLBTP53 | |
| SCHEMBL2335539 | 0.86 | LPAR1 (0.45) | KDM4ELPAR1USP2POLBLPAR2 | |
| SCHEMBL3712290 | 0.86 | NR3C1 (0.38) | KDM4ELPAR1TP53FFAR1MAPT | |
| SCHEMBL3703091 | 0.86 | KDM4E (0.36) | KDM4ELPAR1USP2POLBLPAR2 | |
| SCHEMBL3712524 | 0.85 | LPAR1 (0.42) | KDM4ELPAR1USP2POLBLPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |