SCHEMBL371289

SCHEMBL371289

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nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 2/20 0.31
PKM P14618 1/20 0.31
KDM4E B2RXH2 2/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5140347 0.73
SCHEMBL28401629 0.71 HSD17B10 (0.34) ALDH1A1KMT2AMEN1MAPTHPGD
SCHEMBL5915087 0.69 HDAC3 (0.36) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL275321 0.69 HDAC3 (0.36) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL15375293 0.69 HDAC1 (0.33) TSHR
SCHEMBL14889184 0.68 ALDH1A1 (0.36) ALDH1A1KDM4EMAPTTSHRNPC1
Acetaldehyde SCHEMBL591968 0.67 HTT (0.35) ALDH1A1MAPTTSHRSMN1; SMN2
Octane SCHEMBL1164389 0.67 HDAC1 (0.39) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL15375290 0.67 HDAC1 (0.39) ALDH1A1KMT2AKDM4EMEN1MAPT
SCHEMBL3263283 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2742080-B1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1, 3]DIAZOLE UNITS ENI SPA (IT) 2020-06-17 EP disclosed
US-10312395-B2 Luminescent solar concentrator comprising disubstituted benzoheterodiazole compounds ENI S.P.A. (IT) 2019-06-04 US disclosed
EP-3198658-B1 LUMINESCENT SOLAR CONCENTRATOR COMPRISING DISUBSTITUTED BENZOHETERODIAZOLE COMPOUNDS ENI SPA (IT) 2018-12-12 EP disclosed
US-20170250300-A1 LUMINESCENT SOLAR CONCENTRATOR COMPRISING DISUBSTITUTED BENZOHETERODIAZOLE COMPOUNDS ENI S.P.A. (IT) 2017-08-31 US disclosed
EP-3198658-A1 LUMINESCENT SOLAR CONCENTRATOR COMPRISING DISUBSTITUTED BENZOHETERODIAZOLE COMPOUNDS ENI S.p.A. (IT) 2017-08-02 EP disclosed
US-9440965-B2 Process for the synthesis of benzothiadiazole compounds ENI S.P.A. (IT) 2016-09-13 US disclosed
US-20150291575-A1 PROCESS FOR THE SYNTHESIS OF BENZOTHIADIAZOLE COMPOUNDS ENI S.P.A. (IT) 2015-10-15 US disclosed
US-9150696-B2 Process for the preparation of polymers containing benzohetero [1,3] diazole units ENI S.P.A. (IT) 2015-10-06 US disclosed
EP-2593449-B1 PROCESS FOR THE SYNTHESIS OF BENZOTHIADIAZOLE COMPOUNDS ENI SPA (IT) 2015-09-09 EP disclosed
US-20140235818-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1,3] DIAZOLE UNITS ENI S.P.A. (IT) 2014-08-21 US disclosed
EP-2742080-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1, 3]DIAZOLE UNITS ENI S.p.A. (IT) 2014-06-18 EP disclosed
EP-2593449-A1 PROCESS FOR THE SYNTHESIS OF BENZOTHIADIAZOLE COMPOUNDS ENI S.p.A. (IT) 2013-05-22 EP disclosed
WO-2013021314-A1 PROCESS FOR THE PREPARATION OF POLYMERS CONTAINING BENZOHETERO [1, 3] DIAZOLE UNITS ENI S.P.A. (IT) 2013-02-14 WO disclosed
WO-2012007834-A1 PROCESS FOR THE SYNTHESIS OF BENZOTHIADIAZOLE COMPOUNDS ENI S.P.A. (IT) 2012-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170250300-A1 LUMINESCENT SOLAR CONCENTRATOR COMPRISING DISUBSTITUTED BENZOHETERODIAZOLE COMPOUNDS SCO2, SCLY, SLC39A7 ALDH1A1 2766/4885KMT2A 4798/4885PKM 1726/4885
US-10312395-B2 Luminescent solar concentrator comprising disubstituted benzoheterodiazole compounds SCO2, SLC39A7, SCLY ALDH1A1 3009/4885KMT2A 4799/4885PKM 1858/4885
US-20150291575-A1 PROCESS FOR THE SYNTHESIS OF BENZOTHIADIAZOLE COMPOUNDS LSS, SQLE, SQOR ALDH1A1 1065/4885KMT2A 3296/4885PKM 646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.