Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710270 | 0.86 | ACACB (0.59) | ACACBFFAR1ALDH1A1LMNAHPGD | |
| SCHEMBL3714474 | 0.86 | SMPD1 (0.57) | ACACBPTPN1PTPN6PTPN11NPC1 | |
| SCHEMBL3713623 | 0.84 | MCL1 (0.57) | ACACBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3711389 | 0.84 | ACACB (0.58) | ACACBFFAR1ALDH1A1LMNA | |
| SCHEMBL20510001 | 0.83 | LMNA (0.52) | PTPN1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3713313 | 0.83 | ACACB (0.60) | ACACBNPC1RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL7928394 | 0.80 | MAOB (0.59) | ACACBPTPN1PTPN6PTPN11NPC1 | |
| SCHEMBL15030383 | 0.79 | ACACB (0.61) | ACACBNPC1RAB9ASMN1; SMN2FFAR1 | |
| SCHEMBL3711888 | 0.79 | ACACB (0.60) | ACACBFFAR1ALDH1A1 | |
| SCHEMBL3713066 | 0.79 | ACACB (0.65) | ACACBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |