Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | ACP3 | P15309 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275121 | 0.85 | SIGMAR1 (0.43) | SIGMAR1ACP3POLBSMN1; SMN2MEN1 | |
| SCHEMBL7275120 | 0.85 | SIGMAR1 (0.43) | SIGMAR1ACP3POLBSMN1; SMN2MEN1 | |
| SCHEMBL6601690 | 0.82 | SIGMAR1 (0.49) | SIGMAR1ACP3POLBSMN1; SMN2MAPT | |
| SCHEMBL6601685 | 0.82 | SIGMAR1 (0.49) | SIGMAR1ACP3POLBSMN1; SMN2MAPT | |
| SCHEMBL24019759 | 0.81 | SIGMAR1 (0.47) | SIGMAR1POLBSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL8399376 | 0.81 | SIGMAR1 (0.43) | SIGMAR1ACP3POLBSMN1; SMN2KDM4E | |
| SCHEMBL8399378 | 0.79 | GAA (0.44) | SIGMAR1ACP3SMN1; SMN2MAPTMCL1 | |
| SCHEMBL7746605 | 0.77 | SIGMAR1 (0.55) | SIGMAR1ACP3POLBSMN1; SMN2KDM4E | |
| SCHEMBL7346313 | 0.77 | SIGMAR1 (0.55) | SIGMAR1ACP3POLBSMN1; SMN2KDM4E | |
| SCHEMBL11541322 | 0.76 | SIGMAR1 (0.39) | SIGMAR1ACP3POLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010106441-A2 | PEPTIDOMIMETICS FOR MODULATING INTERLEUKIN-1 RECEPTOR | CENTRE HOSPITALIER UNIVERSITAIRE SAINTE-JUSTINE (CA) | 2010-09-23 | — | — | WO | disclosed |