Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6601690 | 1.00 | SIGMAR1 (0.49) | SIGMAR1PSMB5ALDH1A1MEN1KMT2A | |
| SCHEMBL3713615 | 0.82 | SIGMAR1 (0.47) | SIGMAR1MEN1KMT2APOLBMAPT | |
| SCHEMBL7275121 | 0.79 | SIGMAR1 (0.43) | SIGMAR1MEN1KMT2APOLBANPEP | |
| SCHEMBL8399376 | 0.79 | SIGMAR1 (0.43) | SIGMAR1MEN1KMT2APOLBMAPT | |
| SCHEMBL7275120 | 0.79 | SIGMAR1 (0.43) | SIGMAR1MEN1KMT2APOLBANPEP | |
| SCHEMBL7346313 | 0.78 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7746605 | 0.78 | SIGMAR1 (0.55) | SIGMAR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL8399378 | 0.76 | GAA (0.44) | SIGMAR1ALDH1A1MAPTSMN1; SMN2GAA | |
| SCHEMBL13995594 | 0.76 | SIGMAR1 (0.74) | SIGMAR1ALDH1A1POLB | |
| SCHEMBL13995225 | 0.76 | SIGMAR1 (0.74) | SIGMAR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923569-B1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6020366-A | Butyric acid matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0923569-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006711-A1 | BUTYRIC ACID MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |